Nodejs projects natively use npm as the package manager, which works better with TypeScript (in my experience at least). Unit testing would be made easier as well. Those that would rather use nuget should be able to use .NET Core projects, which also includes native TypeScript unit test support as described in the documentation:

https://docs.microsoft.com/en-us/visualstudio/javascript/unit-testing-javascript-with-visual-studio?view=vs-2019&tabs=mocha