LESS and SASS support
Add the ability to link LESS and SASS files in a Visual Studio solution to CRM. The CSS produced by the LESS and SASS file is what would be published to CRM.

This was added to v4.5.0 in August.
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Thanks for this comment. We would take the approach that you suggested since actually implementing LESS or SASS is not a simple task. We would simply allow you to link the LESS or SASS file but the actual css file produced is what would publish to CRM. We would also provide all the other abilities that other web resource files have in CRM Solution Manager.
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Francis Seits commented
Just use web essentials (http://vswebessentials.com/features/less) for less "auto compiling on save" and link the generated css file to crm